[Comparison of some qualitative and quantitative dermatoglyphic patterns of palm and finger tips between cleft lip/palate and healthy individuals in Bojnurd]

To provide a comprehensive and precise research for population studies on the association of dermatoglyphic patterns on cleft lip/palate deficits. This was a case-control observational study that conducted in North Khorasan on 1386. Using a simple random sampling individuals with cleft/lip palate were allocated to case group and their matched health cases were considered as control. Palm and finger prints were done in the sample. In addition a-b, b-c and c-d counts, atd angel measurement and dermatoglyphics patterns of finger tips of both hands were made and the differences were compared between two groups. Palm prints were studied by an expert for quantitive and qualative characters and Statistical analysis was performed using by SPSS software. Our findings showed that the group and sex did not affect the mean of a-b, b-c, c-d counts and mean of atd angle of right and left hands.The mean of a-b in females and males of both groups were similar [38.63 and 38.89 respectively]. There were no significant differences between TABRC of males and females and right or left hands in both groups. The c-d count and atd angle of right hand was more than the left. The most frequent finger pattern in both hands was loop in both groups. There were no significant differences between two groups regarding the pattern of finger tips of both hands. In contrast of several studies that indicate there are special dermatoglyphic patterns in patients with cleft lip/palate, this study did not find any statistical differences between two groups regarding palm count and finger tips patterns of both hands. Since several environmental and hereditary factors would affect on the disease occurance, there is need to larger studies among different populations

[Morphometric study of the influence of hypo and hyperthyroidism on papillar myocytes at left ventricle of rats]

Thyroid gland affects many physiologic and metabolic activities .Thyroxine [T4] and its effective form [T3] regulate metabolism of tissues. These hormones affect the heart work with direct or indirect mechanisms. In the present study we investigated the effect of hypo and hyperthyroidism on rat heart. We used female Wistar rats [250-300 gr] in 3 groups [each consisted of 6]: Hyperthyroid rats were treated with thyroxine [1 mg/lit water for 20 days] hypothyroid rats were treated with propylthyoacil [PTU] [0.5 gr/lit water] and Control. Finally, histopathological and stereometric evidences were investigated in heart slides. Results showed that in papillar muscle of hyperthyroid rats, there were clear evidences of hypertrophy and increased capillary density. In hypohtyroid rats, however, changes were in opposite to hyperthyroid rats. Results revealed that during changes of hypo and hyperthyroidism, the metabolic changes are in accordance with cardiac hyperthrophy during hyperthyroidism and in opposite direction in hypothyroid rats

Histopathological study of protective Tumeric against toxicity induced by acetaminophen in broiles

Turmeric [Curcuma longa L.] has protective effects on Liver and digestive system. Based on the importance of poultry industry and toxic agents that induce disease in broilers, we studied the protective effect of Turmeric on liver. Pre treatment with turmeric [1 mg/KgB.W] for 14 days and treatment with acetaminophen [650 mg/kgB. W] and turmeric for 30 days were conducted. Determination of daily body weight gain and hystopathological studies on liver, smallintestine and forestomach were conducted. pre treatment with turmeric resulted in better rate of growth and improvement of small intestine mucus. The side effect of acetaminophen was reversed after treatment with the extract. It is suggested that addition of Turmeric to poultry nutrient is very useful for protection against toxins. That reffers to curcumin

effect of plasma testosteron on epileptiform seizures induced by pentylen tetrazole [PTZ] in normal and gonadectomized male rats

It has been verified that androgene concentration in epileptic men who were treated with antiepileptic drugs is decreased and this results in a decrease in sexual activities in such patients. Although there : are many investigations regarding the effects of antileptic drugs on the rate of serum androgenes and particularly testosteron, little is known about the probable effects of androgenes on epileptic seizures. In this study the effects of plasma level of testosteron on epileptiform seizures in three cases [normal, increased and decreased] induced with Pentylentetrazole [PTZ] in Wistar male rats were investigated. Wistar male rats with similar response and sesitivity to PTZ and epileptiform seizures were randomly assigned to the five following: groups [n=8 for each group]. 1[st] exprimental group: Intramuscular injection of testosteron [5 mg/Kg BW] and after 2 hours intraperitoneal injection of PTZ [25mg/Kg BW/for max. 3 times]; 2[nd] exprimental group: treatment with testosteron [0.5 mg/Kg BW] for 10 days and injections of PTZ thereafter; control group for 1[st] and 2[nd] experimental rats where they received sesame oil and then PTZ in a protocol precisely similar to the 1[st] and 2[nd] groups; 3[rd] exprimental group: PTZ injections and recording of epileptiform convulsions before gonadectomy [as control] and repeat of PTZ injections after 10 days. The last protocol was performed in two groups: gonadectomized, without any testosteron injections, and gonadectomized but with one dose of testoteron. The results show that increase in serum testosteron level does not affect epileptiform convulsions, whereas the reduction of testosteron level increases the partial seizures [p<0.001] and duration of tonic-clonic seizures [p<0.05]. Results of this study show that testosteron has an anticonvulsant effect and this effect might be through neurosteroid metabolites, where these metabolites affect on GABA A receptor complex